Author: Truth & Hammer

  • A Secret Garden Behind the Hedge – FineGardening

    A Secret Garden Behind the Hedge – FineGardening

    Welcome to Judy Boyle’s garden!

    Hemlocks (Tsuga canadensis, Zones 3–7), Leyland cypress (× Cupressocyparis leylandii, Zones 6–10), and green giants (Thuja ‘Green Giant’, Zones 5–8) create a privacy border for the backdrop of my half acre. As proud as I am of my lawn and gardens in front of this backdrop, seen from the entire back of the house, I am even more proud of what I’ve accomplished (along with glorious Mother Nature!) behind the backdrop of my Zone 7A garden.

    Three years ago, this was a forgotten section of property behind the wall of evergreens. Fallen branches, dead trees, poison ivy, and discarded stone were strewn everywhere. Little by little, I began clearing the space of all the debris.

    My hubby built this adorable shed, and it’s now in the process of getting landscaped.

    I have mostly planted astilbe, ferns, hydrangeas, rhododendrons, tiger lilies, ajuga, ivy, creeping Jenny, and hostas. There are very few annuals in my garden. For the past few years, I have only planted perennials; otherwise, I’d go totally bankrupt.

    More of the new landscape behind the evergreen wall.

    This is one of the openings from the woods to the main part of the backyard, which is in front of the evergreen wall.

    My hubby built this pond about 20 years ago. It had an abundance of koi for many years, but sadly they perished during a particularly frigid winter, and now we use the pond as a water garden.

    In front of the evergreen wall is a garden filled with grasses, sedum, peonies, iris, and on and on.

    I have been smitten with gardening for 40 years. Every Mother’s Day since my daughter was born more than 30 years ago, I’ve received something special to plant in honor of all moms. I don’t know how I will ever leave my garden. (Here is a weeping blue cedar, Cedrus atlantica ‘Glauca pendula’, Zones 6–9.)

    Have a garden you’d like to share?

    Have photos to share? We’d love to see your garden, a particular collection of plants you love, or a wonderful garden you had the chance to visit!

    To submit, send 5-10 photos to GPOD@finegardening.com along with some information about the plants in the pictures and where you took the photos. We’d love to hear where you are located, how long you’ve been gardening, successes you are proud of, failures you learned from, hopes for the future, favorite plants, or funny stories from your garden.

    If you want to send photos in separate emails to the GPOD email box that is just fine.

    Have a mobile phone? Tag your photos on Facebook, Instagram or Twitter with #FineGardening!

    You don’t have to be a professional garden photographer – check out our garden photography tips!

    Do you receive the GPOD by email yet? Sign up here.

    Get our latest tips, how-to articles, and instructional videos sent to your inbox.

    This content was originally published here.

  • How to keep your home cool without using air conditioning

    How to keep your home cool without using air conditioning

    We all want a cool home when the hot summer months arrive, but using the air-conditioning wastes a lot of energy. Not to mention it can cost a fortune to keep the air-conditioning on. To save yourself some money and the planet, here are a few ways to keep your home chill without flipping on the AC.

    First, open the windows. Creating a cross-breeze is one of the most effective ways to cool a home. The key to effective breeze cooling is figuring out which direction the wind blows. In some areas, it’s fairly consistent, commonly coming from the same direction during the same times each day (most often in the afternoon). Open up windows during that “window” of a breeze to encourage the flow through your home.

    Using blinds is another way to keep your home cool. When your windows are closed, blinds can help stop heat from entering the home through your windows.

    Another effective strategy to keep the sun from injecting blistering heat into a room is to keep it dark. Completely close off rooms when they are not being used. If you don’t mind being left in the dark, install blackout curtains, which effectively block the heat from entering the room through the window. Both ceiling fans and box fans are useful for cooling space without cranking up the energy bill. To create even cooler air, place a container of ice directly in front of the fan. The air from the fan will bounce off the ice and direct the cool air across the room.

    If you’re keen to learn more ways to chill your house without using air-conditioning, have a look right here.

    This content was originally published here.

  • What Are the Benefits of a Humidifier for Your Home? | Molekule Blog

    What Are the Benefits of a Humidifier for Your Home? | Molekule Blog

    During cold winter months (or in the heat of the summer when your AC is on), you may notice that the air in your home is dry. Just like very humid air could be bad news for your health, dry air may cause nose and eye irritation in otherwise healthy people. One solution is to use a humidifier if the air in your home is too dry. Below, you will learn how humidifiers work, the benefits of using one in your home, and how to choose the right one and use it correctly.

    Humidity levels and health benefit

    Very dry and very humid air can affect your health and the condition of your home. When air is too humid, it can encourage mold and mildew growth and contribute to health issues, as well as cause potential damage to your home. If you have asthma or another respiratory illness, dry air may make it worse.

    The Cleveland Clinic reports that dry air may cause problems including:

    Keeping the air in your home from becoming too dry may help with many of these health issues. Depending on where you live, controlling indoor humidity is not always easy. This is where a humidifier may offer benefits. It is best to keep your home’s humidity within an optimal range–not too high and not too low. The Environmental Protection Agency (EPA) recommends that you keep the air in your home between 30 and 50 percent humidity.

    Benefits of using a humidifier during sleep

    Humidifiers may be beneficial for adults and children during sleep. Sleep itself aids in repair, rejuvenation and maintenance of our immune system. Adding a humidifier to your bedroom can bolster the effects sleeping naturally provides. Here are some of the benefits you can get from sleeping with a humidifier in your room.

    Humidifier benefits for snoring and sleep apnea

    Humidifiers may help alleviate dry airways that cause snoring. Snoring results from a constricted airway, resulting in a dry mouth and relaxed throat. This dryness causes the respiratory airways to overcompensate by producing more mucus and therefore more constriction and likelihood of uttering an audible vibration such as snoring. Relieving the causes of snoring, such as dry airways, may help those sleep sounder as well (Stuck et al., 2015).

    Habitual snoring could very well indicate an underlying problem such as sleep apnea. Typically this breathing condition would be treated with the use of a CPAP machine in the most severe of cases. Those with snoring issues or sleep apnea could benefit from adding a humidifier to the CPAP treatment. The American Sleep Apnea Association suggests adding a heated humidification (HH) with CPAP to mitigate some problematic features of the CPAP. However, research has shown that HH may not influence CPAP users to continue to use CPAP nor improve sleep itself, but it does improve naso-pharngeal symptoms. (Yu et al., 2012). Since the nasopharynx is part of the nasal cavity of our respiratory system, symptoms such as swelling of the lymph nodes or any other obstruction in this area may cause snoring. We can deduce that those who snore from a naso-pharngeal symptom, may find a heated humidifier useful.

    Too much humidity can disturb sleep

    Studies by NASA indicate that the ideal humidity level for the optimal sleep condition is between 50-60% (Flynn-Evans, Caddick & Gregory, 2016). Though there are benefits to using a humidifier during sleep excessive use may actually disrupt sleep patterns. For example, high humidity alters the perception of the room temperature of an enclosed room; the higher the humidity, the hotter the room feels to us. Conversely, if both humidity and heat are elevated, the sweat response will become disrupted, preventing the natural cooling relief of evaporation when we sweat. This can decrease REM and cause you to stay awake. (Okamoto-Mizuno & Mizuno, 2012)

    Humidifier benefits for babies and children

    For babies and young children, dry air could cause health issues. Using a humidifier may help keep the air within acceptable moisture levels. The main benefits of using a humidifier for babies and kids include:

    Of course, your child does not need to be sick or have dry skin to possibly benefit from the use of a humidifier. Moist air in the right amounts may be beneficial for health and could potentially help keep them from getting sick.

    Other humidifier benefits in your home beyond health

    A humidifier may provide benefits to your home, as well.

    Possible benefits of a humidifier in the spring and summer

    Depending on where you live, the weather may have an impact on when the air in your home feels dry. For example, if you live somewhere with high levels of outdoor humidity, you probably run your air conditioner a lot in the summer. Air conditioning may dry out your home’s air. Using a humidifier may help counteract this. If you live somewhere with dry air, a humidifier might be good to use year-round.

    Since pollen and mold counts tend to be higher in the spring and summer, using a humidifier in your home may also help keep your sinuses from becoming inflamed.

    Which humidifiers to choose?

    There are five main categories of humidifiers. Each works in a different way but the end goal for all of them—adequate moisture conditions in your home—is the same. The type you should choose depends on your needs. Let us take a look.

    Pros and cons of using cool mist or warm mist humidifiers

    Humidifiers release either warm or cool air to help add humidity to a room. Either type could be beneficial, though they each have pros and cons. Which you choose could depend on whether you have children or pets, how big your space is, and your personal preferences.

    Some of the benefits and drawbacks of cool mist humidifiers include:

    The benefits and disadvantages of warm mist humidifiers are:

    Tips for using a humidifier in your home

    Any time you use a humidifier, you should take care to use it properly. Not only will this extend the life of your humidifier, it can ensure that you and your home receive benefits and are not adversely affected.

    change-water-humidifier

    It is clear that dry air can affect your health. Adding a bit of moisture to the air with a humidifier can be an easy solution to this problem. Take care not to use one excessively so that moisture levels are too high, which can encourage mold and dust mite problems. Using an air purifier at the same time can also help improve indoor air quality.

    This content was originally published here.

  • How To Keep Rabbits From Eating Everything In Your Garden

    How To Keep Rabbits From Eating Everything In Your Garden

    Rabbits are voracious eaters and they can wipe out an entire area of new growth overnight.

    How to keep rabbits from eating everything in your garden even if nothing else you’ve tried has worked.

    Have you had the unpleasant experience of visiting your garden in the morning only to find that your tender young shoots have been cut off overnight, as if with a pair of shears?

    If so, you may have had a nighttime visit from a rabbit or two. Rabbits are cute to look at, but they can be a real nuisance to gardeners. Known to be voracious eaters, they can wipe out an entire area of new growth overnight.

    Because they have both upper and lower incisors, rabbits tend to make a clean cut on a stalk when they eat. However, other telltale signs of rabbits in your garden are pea-sized droppings in and around the garden, and chewed tree bark close to ground level. Moreover, tufts of fur on branches and areas that reveal digging activity or even bedding down also can be signs of rabbits.

    Rabbits are timid animals and do not like to stray far from cover. Therefore, one way to discourage them from getting into your garden is to eliminate hiding places such as areas with tall grass and piles of stone or brush.

    Another idea is to plant alfalfa or clover outside your garden area. Rabbits are particularly fond of these two plants and may remain there for their meal– especially if it feels safer — instead of bothering your other plants.

    One more plan of action to deter rabbits is to add some plants to your garden that rabbits dislike. Rabbits tend to go for tender shoots and tender woody plants that have a thin bark, so your young plants are at the highest risk of being eaten. However, if you place some less attractive plants among the ones that the long-eared guys like, they may stay away from your garden.

    How To Keep Rabbits From Eating Everything In Your Garden

    Generally, rabbits dislike plants that have a strong fragrance or have fuzzy leaves. A determined rabbit may simply graze around the plants he does not like, but here are seven garden plants that repel rabbits.

    Plant lavender to keep rabbits from eating everything in your garden.

    1. Veronica –

    With its pretty flowering spikes of blue, pink or white, veronica adds some height (one to two feet) and texture to your garden. Veronica prefers full or part sun and well-drained soil. In addition, the bunnies don’t like it.

    2. Lavender

    You may love the fragrance of lavender, but rabbits do not. This tough beauty can withstand both heat and drought. You can plant it as single plants or form a hedge with many plants to deter pesky bunnies. Lavender prefers full sun and well-drained, slightly alkaline soil.

    3. Siberian Iris

    This elegant iris variety has gorgeous purple, rose, blue or white blooms and big, grassy foliage. It adds beauty to your garden while potentially deterring rabbits. The Siberian iris grows from one to three feet tall and prefers full or part sun and well-drained soil.

    4. Salvia –

    With a wide variety of bold colors to choose from, salvia is a colorful addition to your garden. Try it as a border plant to keep rabbits from entering your vegetable garden. Salvia likes full sun and well-drained soil. Furthermore, it can grow from one to even five feet tall, depending on the variety you choose.

    5. Peony

    They take a while to establish themselves from new roots, but when they do, peonies are a joy to behold. With large, late, springtime flowers and a beautiful variety of colors, peonies are an attractive addition to your garden. What’s even better is that rabbits do not like their tough foliage. Peonies like full sun and well-drained soil and can grow up to seven feet, depending on the variety of plant.

    6. Verbena

    Lovely verbena can grow from a mere six inches to three feet in height. It produces delicate pink, red, white or blue flowers, depending on the variety you select. Surprisingly, rabbits do not like the way verbena smells and usually will steer clear of the plant. Also, verbena prefers full sun and well-drained soil.

    7. Daylily

    Easy to grow and maintain, daylilies come in a rainbow variety of shades. They like full sun and well-drained soil and can grow up to six feet tall. Rabbits do not like their thick stalks.

    Keep in mind that if your long-eared nighttime visitors are hungry enough, they will eat almost anything green in your garden. However, your plants are particularly attractive to rabbits when they are young and tender. Once your plants are established, they are less tempting, and, as a result, other plants may more easily discourage rabbits. We’ll. I hope you’ve learned how to keep rabbits from eating everything in your garden. If you have any tips you would like to share with other readers, please leave them below. Thanks!

    Deer Hate These 7 Plants (So Plant Them Around Your Garden)

     

    This content was originally published here.

  • French Billionaires Haven’t Paid ‘One Cent’ Toward Rebuilding Notre Dame

    French Billionaires Haven’t Paid ‘One Cent’ Toward Rebuilding Notre Dame

    French donors and the French state have also contributed a great deal of money that will go toward the reconstruction of Notre Dame. And that’s extremely important, because there is so much work to do. 

    There were an estimated 300 tons of lead that melted or were otherwise released into the atmosphere during the fire. High levels of lead have now been found in the soil and nearby buildings on the island where the church is located. Up to 150 workers have been tirelessly cleaning toxic lead dust from the cathedral to restore not just the church but the entire surrounding environment to its clean, original state.

    This content was originally published here.

  • Dear Adult Children, Your Parents Don’t Owe You Anything

    Dear Adult Children, Your Parents Don’t Owe You Anything

    Smiling woman stirring food by family in utensilI recently caught up with a girlfriend whom I hadn’t seen in a while. We engaged in our usual girlish chatter, which eventually gave way to our obligatory, “How are your parents?” question. Little did I know, that question would open the floodgates for complaints. My girl —who just like me, is knocking on 30s door— was in her feelings because her father had stopped paying her car note several months ago since he’s gearing up for retirement. I was stunned, not by the fact that her pops was still paying her car note, but by how ungrateful she sounded. Instead of being appreciative of her father for providing financial support that he definitely did not have to provide, she was dogging him because the gravy train was coming to an end. If your parents are still willing to pick up a bill for you, accept the help and be gracious about it. However, to act as if they’re somehow obligated to do so? Miss me with that.

    I wish I could say that my girl’s attitude was unique, but it’s not. So many of my peers (and adult children in general) have a misguided sense of entitlement that is absolutely nauseating. I know a woman who will jump on Facebook in a heartbeat to sub her mom for not being available to babysit her kids. I know a man who is well over 40 who will badger his elderly mother for something nonstop until she caves from simply not wanting to deal with the stress of his presence anymore.

    Here’s the reality: Our parents are getting older with each passing day. They will not be here forever. Instead of being a constant source of stress and drama, we should be the ones lightening the load for them. They have already done their jobs of raising us. It’s okay to ask for and accept help but to act as if we’re somehow owed something is dysfunctional and manipulative. It’s time to grow up.

    Follow Jazmine on Twitter @and visit her blog, Black Girl Mom.

    This content was originally published here.

  • Jervois completes merger with M2 Cobalt – MINING.COM

    Jervois completes merger with M2 Cobalt – MINING.COM

    Image courtesy of Jervois Mining

    Jervois Mining Ltd. (ASX: JRV) today completed its previously announced merger with M2 Cobalt Corp. (TSXV: MC) following receipt of approvals from both M2 Cobalt shareholders and the BC Supreme Court.

    In light of the merger, Simon Clarke, former CEO and executive director of M2 Cobalt, joins the Jervois board as a non-executive director. He is a qualified CPA and securities lawyer with 25 years of senior management experience in the resource and energy sector with companies like OSUM Oil Sands and RailPower Technologies.

    Also at Jervois, Stephen van der Sluys has stepped down as the director and interim CEO for the transition period, while Andy Eldelmeier, former CFO of M2 Cobalt, joins the team as interim CFO. Edelmeier was a partner at Strata Partners, a London-based corporate finance firm, where he advised on private equity financings and cross border M&A.

    Earlier this year, Jervois also entered into an at-market merger with eCobalt Solutions Inc., which will require shareholder approval on July 18, 2019. Following the mergers Jervois will be listed on the ASX and TSXV under the symbol JRV.

    Acquiring M2 Cobalt gives Jervois access to the historic Kilembe mine and Kasese cobalt refinery in Uganda to support the company’s East African ambitions, the company says.

    Written with material from Newsfilecorp.

    This content was originally published here.

  • Trump, launching re-election bid, says Democrats ‘want to destroy our country’

    Trump, launching re-election bid, says Democrats ‘want to destroy our country’

    ORLANDO, Fla. — President Donald Trump accused Democrats of trying to “destroy our country” as he officially kicked off his re-election campaign with a packed-house rally at the Amway Center here Tuesday night.

    “Our radical Democrat opponents are driven by hatred, prejudice and rage,” he said, pointing to House efforts to investigate his 2016 campaign’s ties to Russia and possible obstruction of justice by the president. “They want to destroy you and they want to destroy our country as we know it. Not acceptable, it’s not going to happen. Not going to happen.”

    The federal Russia probes aren’t just an attack on him, he told the crowd — “they are really going after you … They tried to erase your vote, erase your legacy of the greatest campaign and the greatest election probably in the history of our country.”

    Trump officially kicks off 2020 campaign in Florida

    But in the political version of a revival meeting, Trump stuck mostly to familiar rounds of call and response.

    One after another, he delivered familiar applause lines designed to induce chants — “build the wall,” “CNN sucks” and “lock her up” among them — that have been mainstays of his campaign rallies for four years now.

    The tenor of Trump’s remarks wasn’t a huge surprise to observers. His strategy for re-election, say allies, isn’t based on persuading a significant share of the majority of Americans who disapprove of his job performance to vote for him. Rather, he’s trying to super-charge his fans with enough energy that they show up in force for him and spread the word to their friends and neighbors.

    Instead, given both his inability to improve his approval ratings and Democrats’ failure to diminish them, Trump’s remarks appeared designed to appeal to the subset of potential voters already attracted to the messages he’s been driving all along.

    That goal was evident in his decision to aim a message directly at his base during an appearance in Orlando, which sits at the heart of Florida’s I-4 corridor. The region is a traditional swing area in a swing state that is crucial to Trump’s fate, and his answer to that challenge was pumping up his existing supporters rather than reaching out across the political divide.

    Rep. Stephanie Murphy, D-Fla., a leader of the moderate Blue Dog Democrats who represents a neighboring district, said Trump came to the right place, and that her party will have to find the right mix of swing voter outreach and base Democratic enthusiasm to defeat him.

    “President Trump is strategic to target central Florida in his re-election campaign,” Murphy told NBC News. “In order for Democrats to win statewide, we need to recognize the complexities of our Democratic base, while also developing a strategic, well-funded, and well-organized effort to persuade voters, especially independent voters in central Florida.”

    Her concern, she said, is that members of her own party are playing into Trump’s characterizations of Democrats as too hidebound and too far to the left.

    “America will never be a socialist country,” Trump said Tuesday night. “Republicans do not believe in socialism. We believe in freedom, and so do you.”

    Amid sagging poll numbers, Trump begins re-election

    Murphy, who has been vocal in her criticism of the handful of her colleagues who embrace “Democratic socialism,” said her party is in peril of helping Trump win a second term.

    “National Democrats need to realize that what may be good politics in the Bronx or California can backfire in states like Florida,” she said. “Simply put, if we want to beat Donald Trump, we must put winning over political purity.”

    While Trump played all the classic refrains for the faithful, he did hit a few new or rarely used notes in a speech that ran for more than 80 minutes, including a brief appearance by departing White House Press Secretary Sarah Sanders.

    The biggest wrinkle was the voice vote Trump held on whether to maintain his old slogan “Make America Great Again” or change it to “Keep America Great.” The video boards on the sides of the arena featuring the latter strongly hinted at which choice his supporters were expected to pick.

    “Keep America Great” won by a vocal landslide.

    And then Trump told the crowd what it had come to hear.

    “With every ounce of heart and might and sweat and soul, we’re going to keep making America great again and then we will indeed keep America great,” he said. “We will keep it so great, better than ever before. We’re going to keep it better than ever before. And that is why tonight I stand before you to officially launch my campaign for a second time as president of the United States.”

    This content was originally published here.

  • Spider Eating a Pygmy Possum Is Obviously Australian

    Spider Eating a Pygmy Possum Is Obviously Australian

    That’s a photo of a huntsman spider eating a pygmy possum. Yikes!

    A woman named Justine Latton posted this photo in a public Facebook group dedicated to discussing the invertebrates inhabiting the Australian island of Tasmania. Her husband, Adam, spotted the brutal meal at a ski lodge in the island’s Mount Field National Park a few weeks ago, she explained to Gizmodo in a Facebook message.

    “Pygmy possums are quite common up there,” Latton said. “We reckon the spider probably just saw an opportunity and went for it!”

    Huntsman spiders are large arachnids named for the way they actively hunt for their prey. They typically feed on invertebrates and sometimes larger animals like lizards.

    Pygmy possums are nocturnal, mouse-sized marsupials found in Oceania. Though it’s not clear which species of pygmy possum we’re looking at here (I’ve reached out to experts for help identifying it), the island has two species, the Eastern pygmy possum and the Tasmanian pygmy possum. The latter is the smallest possum in the world. Also, as a note to American readers, possums are a family of animals only distantly related to the Western Hemisphere opossums, and are in fact named due to their resemblance to our opossums.

    Gizmodo writer Matt Novak tells me that I should remind readers that not all Australian creatures are scary; some are quite cute. However, we all know that the continent is loaded with deadly snakes, octopuses with enough poison to kill humans, nightmare-inducing spiders, and bees that are even scarier than the spiders.

    So it should surprise no one that the country also produced a possum-eating spider inside of a ski lodge. Ultimately, visitors caught and released the pair, Latton explained, “But no spiders were harmed in the relocation effort (too late for the possum).”

    This content was originally published here.

  • Breakthrough paves way for new Lyme disease treatment

    Breakthrough paves way for new Lyme disease treatment

    Breakthrough paves way for new Lyme disease treatment

    Monique Calello Staunton News Leader
    Published 4:35 PM EDT Jun 17, 2019
    Dr. Brandon Jutras, assistant professor in the Department of Biochemistry, poses for a portrait in his lab.
    Olivia Coleman/Submitted

    A Virginia Tech biochemist has discovered the cellular component that contributes to Lyme arthritis, a debilitating and extremely painful condition that is the most common late stage symptom of Lyme disease, a press release said.

    According to the release from Virginia Tech, the biochemist, Brandon Jutras, found that as the Lyme-causing bacteria borrelia burgdorferi multiplies, it sheds a cellular component called peptidoglycan that elicits a unique inflammatory response in the body.

    “This discovery will help researchers improve diagnostic tests and may lead to new treatment options for patients suffering with Lyme arthritis,” said Jutras, lead author on the study. “This is an important finding and we think that it has major implications for many manifestations of Lyme disease, not just Lyme arthritis.”

    Lyme disease is the most reported vector-borne disease in the country, and in Virginia reports have increased by more than 6,000 percent in the last fifteen years. The Centers for Disease Control, estimates that approximately 300,000 people are diagnosed with Lyme disease annually in the United States. Scientists predict that the number of people who become infected Lyme will increase as our climate continues to change.

    Jutras — an assistant professor of biochemistry in the College of Agriculture and Life Sciences and an affiliated faculty member of the Fralin Life Sciences Institute — and his collaborators recently published their findings in the Proceedings of the National Academy of Sciences.

    According to the release, the PNAS paper was four years in the making, and Jutras began this research during his post-doctoral fellowship in the lab of Christine Jacobs-Wagner, a Howard Hughes Medical Institute Investigator and professor at Yale University.

    Castor bean tick. Dangerous parasitic insect. Carrier of infections as encephalitis and Lyme borreliosis.
    Ladislav Kubeš, Getty Images/iStockphoto

    “Nowadays nothing significant in science is accomplished without collaboration,” said Jutras. Co-authors on this paper ranged from bench scientists to medical doctors and practicing physicians. Dr. Allen Steere, a Harvard doctor who originally identified Lyme disease in the 1970s, assisted Jutras with his research and provided access to patient samples.

    The research could provide a new way to diagnose Lyme disease and Lyme arthritis for patients with vague symptoms based on the presence of the cellular component called peptidoglycan in synovial fluid.

    The press release said, the team found peptidoglycan is a major contributor to Lyme arthritis in late-stage Lyme disease patients. Peptidoglycan is an essential component of bacterial cell walls. All bacteria have some form of peptidoglycan, but the form found in the bacteria that causes Lyme, borrelia burgdorferi, has a unique chemical structure. When the bacteria multiply, they shed peptidoglycan into the extracellular environment, because its genome does not have the appropriate proteins to recycle it back into the cell.

    Read: Every spot in Virginia is a hotspot for ticks

    “We can actually detect peptidoglycan in the synovial fluid of the affected, inflamed joints of patients that have all the symptoms of Lyme arthritis but no longer have an obvious, active infection,” said Jutras in the release.

    Peptidoglycan elicits an inflammatory response and the molecule persists in the synovial fluid, which means that our bodies continue to respond, without mounting a counter response.

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    Receptors in our immune system sense bacterial products and, depending on the individual’s genetic predispositions, may determine how strongly a patient’s body reacts to peptidoglycan.

    The next phase of Jutras’ work is to use methods to destroy the peptidoglycan, or intervene to prevent a response, which could get rid of Lyme disease symptoms. According to the release, Jutras predicts that with either therapy patients would start recovering sooner.

    Clinical samples included in this study were obtained from patients that had confirmed cases of Lyme disease under the guidelines of the CDC, but virtually all did not respond to oral and/or intravenous antibiotic treatment, the release said. The presence of peptidoglycan in these patients’ synovial fluids may explain why some people experience symptoms of late stage Lyme disease in the absence of an obvious infection. In this case, the usual antibiotic treatments for Lyme disease would no longer be helpful, but this discovery might provide avenues for new treatments, the press release said.

    Read: Risk of lyme disease is higher here. The effects can be devastating.

    Members of the Jacobs-Wagner lab purified the peptidoglycan and removed all other bacterial components and asked: is peptidoglycan all on its own capable of causing arthritis in a mouse model?

    According to the release, within 24 hours post-injection, mice presented with dramatic joint inflammation, indicating that peptidoglycan can cause arthritis.

    Jutras is continuing his research at Virginia Tech on peptidoglycan by more thoroughly studying its chemical composition to determine how it is able to persist in the human body. This will also help further the understanding of how this bacterial product contributes to other manifestations of Lyme disease.

    “We are interested in understanding everything associated with how patients respond, how we can prevent that response, and how we could possibly intervene with blocking therapies or therapies that eliminate the molecule entirely,” Jutras said.

    Read: Roadblocks limit Virginia patient access to marijuana

    Read: Medical marijuana policies at 5 Virginia hospitals

    What should we know about health care in this community? Let health reporter Monique Calello know at mcalello@newsleader.com and follow her on Twitter and Instagram @moniquecalello.

    This content was originally published here.